Reviews Winter 2020

Book Reviews, Winter 1980

CNS Drug Reviews, Vol. 4, No. 4, Winter 1998

The Satellite Symposium “Glial cells in Aging and Neurodegeneration” was organized by The National Institute of Aging (NIA) and held in the Los Angeles Convention Hall on Saturday, November 7, 1998. It consisted of six lectures by distinguished scientists from leading American Universities, whose research was supported by NIA. A. Peters (Boston Univ., Boston, MA) discussed the effects of aging ...

CNS Drug Reviews, Vol. 4, No. 4, Winter 1998

Each of us spends approximately one third of our life sleeping. Thanks to technological advances in methods of evaluating the electrical activity of the brain during sleep and wakefulness (polysomnography) we now know a great deal about the physiology of sleep in humans and lower animals. We know less about the functions of sleep, however, although there has never been any shortage of theory an...

CNS Drug Reviews, Vol. 4, No. 4, Winter 1998

The discovery of zonisamide (ZNS) did not result from a search for new antiepileptic drug (AED). A continuous random screening for anticonvulsant activity had been in progress for many years at the research laboratories of Dainippon Pharmaceutical Co., Ltd. ZNS was discovered by serendipity in 1974 during routine testing of 1,2-benzisoxazole derivatives which were synthesized for the management...

CNS Drug Reviews, Vol. 4, No. 4, Winter 1998

This year’s University of Southern California (USC) neuroscience symposium spotlighted the emerging roles of glial cells in neural development, function, and regeneration, as well as in neurodegenerative diseases. The recent explosion in the knowledge of glial function has established that, contrary to the traditional view of glia as passive supporting cells, glia are active partners to neurons...